Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation

Background: Many patients with familial adenomatous polyposis (FAP) die from desmoid tumours which can arise spontaneously but often appear to be surgically induced by prophylactic colectomy. FAP results from germline adenomatous polyposis coli (APC) gene mutations and desmoids arise following biall...

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Detalhes bibliográficos
Main Authors: Sturt, N J H, Gallagher, M C, Bassett, P, Philp, C R, Neale, K F, Tomlinson, I P M, Silver, A R J, Phillips, R K S
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by Gut 2004
Assuntos:
Colon Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774338/
https://ncbi.nlm.nih.gov/pubmed/15542524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.042705
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