Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation

Background: Many patients with familial adenomatous polyposis (FAP) die from desmoid tumours which can arise spontaneously but often appear to be surgically induced by prophylactic colectomy. FAP results from germline adenomatous polyposis coli (APC) gene mutations and desmoids arise following biall...

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Tallennettuna:
Bibliografiset tiedot
Päätekijät: Sturt, N J H, Gallagher, M C, Bassett, P, Philp, C R, Neale, K F, Tomlinson, I P M, Silver, A R J, Phillips, R K S
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Copyright 2004 by Gut 2004
Aiheet:
Colon Cancer
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1774338/
https://ncbi.nlm.nih.gov/pubmed/15542524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gut.2004.042705
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