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Structure–Activity Relationships and Molecular Modeling of 3,5-Diacyl-2,4-dialkylpyridine Derivatives as Selective A(3) Adenosine Receptor Antagonists

The structure-activity relationships of 6-phenyl-1,4-dihydropyridine derivatives as selective antagonists at human A(3) adenosine receptors have been explored (Jiang et al. J. Med. Chem. 1997, 39, 4667-4675). In the present study, related pyridine derivatives have been synthesized and tested for aff...

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Detalhes bibliográficos
Main Authors: Li, An-Hu, Moro, Stefano, Melman, Neli, Ji, Xiao-duo, Jacobson, Kenneth A.
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474377/
https://ncbi.nlm.nih.gov/pubmed/9703464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm980093j
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