Caricamento...

Triple stimulus-responsive polypeptide nanoparticles that enhance intratumoral spatial distribution

To address the limited tumor penetration of nanoparticle drug delivery vehicles, we report the first pH-responsive polypeptide micelle that dissociates at the low extracellular pH of solid tumors. This histidine-rich elastin-like polypeptide block copolymer (ELP(BC)) self-assembles at 37°C into sphe...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Callahan, Daniel J., Liu, Wenge, Li, Xinghai, Dreher, Matthew R., Hassouneh, Wafa, Kim, Minkyu, Marszalek, Piotr, Chilkoti, Ashutosh
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474318/
https://ncbi.nlm.nih.gov/pubmed/22417133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nl300630c
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !