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The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA
Genome-wide genotyping of a cohort using pools rather than individual samples has long been proposed as a cost-saving alternative for performing genome-wide association (GWA) studies. However, successful disease gene mapping using pooled genotyping has thus far been limited to detecting common varia...
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| 主要な著者: | , , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3474315/ https://ncbi.nlm.nih.gov/pubmed/21424828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-0974-0 |
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