The efficacy of detecting variants with small effects on the Affymetrix 6.0 platform using pooled DNA

Genome-wide genotyping of a cohort using pools rather than individual samples has long been proposed as a cost-saving alternative for performing genome-wide association (GWA) studies. However, successful disease gene mapping using pooled genotyping has thus far been limited to detecting common varia...

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主要な著者: Chiang, Charleston W. K., Gajdos, Zofia K. Z., Korn, Joshua M., Butler, Johannah L., Hackett, Rachel, Guiducci, Candace, Nguyen, Thutrang T., Wilks, Rainford, Forrester, Terrence, Henderson, Katherine D., Le Marchand, Loic, Henderson, Brian E., Haiman, Christopher A., Cooper, Richard S., Lyon, Helen N., Zhu, Xiaofeng, McKenzie, Colin A., Palmer, Mark R., Hirschhorn, Joel N.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3474315/
https://ncbi.nlm.nih.gov/pubmed/21424828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-0974-0
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