Use of weighted reference panels based on empirical estimates of ancestry for capturing untyped variation

Many association methods use a subset of genotyped single nucleotide polymorphisms (SNPs) to capture or infer genotypes at other untyped SNPs. We and others previously showed that tag SNPs selected to capture common variation using data from The International HapMap Consortium (Nature 437:1299–1320,...

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Main Authors: Egyud, Matthew R. L., Gajdos, Zofia K. Z., Butler, Johannah L., Tischfield, Sam, Le Marchand, Loic, Kolonel, Laurence N., Haiman, Christopher A., Henderson, Brian E., Hirschhorn, Joel N.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3126674/
https://ncbi.nlm.nih.gov/pubmed/19184111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-009-0627-8
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