Molecular cloning of 3-hydroxy-3-methylglutaryl coenzyme a reductase and evidence for regulation of its mRNA.

A recombinant plasmid containing a 1.2-kilobase cDNA for 3-hydroxy-3-methylglutaryl coenzyme A reductase was isolated from a cDNA library prepared from UT-1 cells, a clone of Chinese hamster ovary cells that has markedly elevated reductase activity. This plasmid, designated pRed-10, was identified b...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Chin, D J, Luskey, K L, Faust, J R, MacDonald, R J, Brown, M S, Goldstein, J L
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1982
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347416/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6961444/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.24.7704
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