Tumor promoter phorbol 12-myristate 13-acetate induces a clastogenic factor in human lymphocytes.
The mechanism of the clastogenic action--i.e., the ability to induce chromosomal aberrations--of the tumor promoter phorbol 12-myristate 13-acetate (PMA) was investigated. PMA at 10 and 100 ng/ml induced the formation of a low molecular weight (less than 10,000) clastogenic factor (CF) in phytohemag...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1982
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347369/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6818546/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7509 |
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