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Tumor promoter phorbol 12-myristate 13-acetate induces a clastogenic factor in human lymphocytes.

The mechanism of the clastogenic action--i.e., the ability to induce chromosomal aberrations--of the tumor promoter phorbol 12-myristate 13-acetate (PMA) was investigated. PMA at 10 and 100 ng/ml induced the formation of a low molecular weight (less than 10,000) clastogenic factor (CF) in phytohemag...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Emerit, I, Cerutti, P A
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1982
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347369/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6818546/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7509
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