Phase I Trial of Induction Histone Deacetylase and Proteasome Inhibition Followed by Surgery in Non-small Cell Lung Cancer

INTRODUCTION: Despite complete surgical resection survival in early stage non-small cell lung cancer (NSCLC) remains poor. Based on prior pre-clinical evaluations, we hypothesized that combined induction proteasome and histone deacetylase inhibitor therapy, followed by tumor resection, is feasible....

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Detalhes bibliográficos
Main Authors: Jones, David R., Moskaluk, Christopher A., Gillenwater, Heidi H., Petroni, Gina R., Burks, Sandra G., Philips, Jennifer, Rehm, Patrice K., Olazagasti, Juan, Kozower, Benjamin D., Bao, Yongde
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473142/
https://ncbi.nlm.nih.gov/pubmed/23059775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e318267928d
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