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Inactivating all three Rb family pocket proteins is insufficient to initiate cervical cancer

HPV-16 is associated etiologically with many human cervical cancers. It encodes three oncogenes E5, E6 and E7. Of these oncogenes, E7 has been found to be the dominant driver of cervical cancer in mice. Over 100 cellular proteins have been reported to associate with HPV-16 E7, which is thought to dy...

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Main Authors: Shin, Myeong-Kyun, Sage, Julien, Lambert, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473120/
https://ncbi.nlm.nih.gov/pubmed/22942253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-2083
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