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Variation in OPRM1 Moderates the Effect of Desire to Drink on Subsequent Drinking and its Attenuation by Naltrexone Treatment

To evaluate the role of the functional Asn40Asp polymorphism in the mu-opioid receptor gene on drinking behavior and naltrexone’s ability to attenuate drinking, we used a daily diary method in a 12-week, randomized clinical trial of naltrexone to reduce drinking. Participants (N=158 problem drinkers...

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Detalhes bibliográficos
Main Authors: Kranzler, Henry R., Armeli, Stephen, Covault, Jonathan, Tennen, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473112/
https://ncbi.nlm.nih.gov/pubmed/22784013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2012.00471.x
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