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Variation in OPRM1 Moderates the Effect of Desire to Drink on Subsequent Drinking and its Attenuation by Naltrexone Treatment

To evaluate the role of the functional Asn40Asp polymorphism in the mu-opioid receptor gene on drinking behavior and naltrexone’s ability to attenuate drinking, we used a daily diary method in a 12-week, randomized clinical trial of naltrexone to reduce drinking. Participants (N=158 problem drinkers...

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Autori principali: Kranzler, Henry R., Armeli, Stephen, Covault, Jonathan, Tennen, Howard
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3473112/
https://ncbi.nlm.nih.gov/pubmed/22784013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2012.00471.x
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