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Affinity chromatography of human platelet α(2)-adrenergic receptors

Catecholamines, such as epinephrine, inhibit the enzyme adenylate cyclase (EC 4.6.1.1) via a specific receptor mechanism involving α(2)-adrenergic receptors. In order to facilitate purification of these inhibitory receptors we have prepared a highly effective biospecific affinity adsorbent. The immo...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Regan, John W., Barden, Nicholas, Lefkowitz, Robert J., Caron, Marc G., DeMarinis, Robert M., Krog, Arnold J., Holden, Kenneth G., Matthews, William D., Hieble, J. Paul
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1982
Soggetti:
Biological Sciences: Biochemistry
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347311/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6130523/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.23.7223
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