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Local mutagenesis within deletion loops of DNA heteroduplexes.

An efficient method has been developed to generate base substitution mutations within deletion loops of DNA heteroduplexes. This method utilizes a heteroduplex formed between a deletion mutant cloned in a plasmid vector and its wild-type counterpart from which two restriction sites had been removed...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Peden, K W, Nathans, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC347309/
https://ncbi.nlm.nih.gov/pubmed/6760191
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