Selective Inhibition of HER2-Positive Breast Cancer Cells by the HIV Protease Inhibitor Nelfinavir

BACKGROUND: Human epidermal growth factor receptor 2 (HER2)–positive breast cancer is highly aggressive and has higher risk of recurrence than HER2-negative cancer. With few treatment options available, new drug targets specific for HER2-positive breast cancer are needed. METHODS: We conducted a pha...

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Huvudupphovsmän: Shim, Joong Sup, Rao, Rajini, Beebe, Kristin, Neckers, Len, Han, Inkyu, Nahta, Rita, Liu, Jun O.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472971/
https://ncbi.nlm.nih.gov/pubmed/23042933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djs396
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