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Specific cleavage of the p15A primer precursor by ribonuclease H at the origin of DNA replication.

We report studies on the mechanism of initiation of DNA replication by p15A, a small plasmid whose origin of replication is known to function much as does that of ColE1. Previous work has shown that an RNA primer for DNA synthesis is generated by the action of RNase H (EC 3.1.26.4) on a precursor tr...

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Autors principals: Selzer, G, Tomizawa, J I
Format: Artigo
Idioma:Inglês
Publicat: 1982
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC347282/
https://ncbi.nlm.nih.gov/pubmed/6185945
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