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Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time

Cilia are necessary for sonic hedgehog (Shh) signaling, which is required to pattern the neural tube. We know that ventral neural cell fates are defined by a specific cohort of transcription factors that are induced by distinct thresholds of Shh activity mediated by opposing gradients of Gli activat...

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Detalhes bibliográficos
Main Authors: Su, Chen-Ying, Bay, Sarah N., Mariani, Laura E., Hillman, Michael J., Caspary, Tamara
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472586/
https://ncbi.nlm.nih.gov/pubmed/23014696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.082321
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