Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress

BACKGROUND: HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced the endogenous hacA gene of an Aspergillus niger strain...

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Detalhes bibliográficos
Main Authors: Carvalho, Neuza DSP, Jørgensen, Thomas R, Arentshorst, Mark, Nitsche, Benjamin M, van den Hondel, Cees AMJJ, Archer, David B, Ram, Arthur FJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472299/
https://ncbi.nlm.nih.gov/pubmed/22846479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-350
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