Genome-wide expression analysis upon constitutive activation of the HacA bZIP transcription factor in Aspergillus niger reveals a coordinated cellular response to counteract ER stress

BACKGROUND: HacA/Xbp1 is a conserved bZIP transcription factor in eukaryotic cells which regulates gene expression in response to various forms of secretion stress and as part of secretory cell differentiation. In the present study, we replaced the endogenous hacA gene of an Aspergillus niger strain...

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Autori principali: Carvalho, Neuza DSP, Jørgensen, Thomas R, Arentshorst, Mark, Nitsche, Benjamin M, van den Hondel, Cees AMJJ, Archer, David B, Ram, Arthur FJ
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472299/
https://ncbi.nlm.nih.gov/pubmed/22846479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-350
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