Nuclear Factor kappa B is central to Marek’s Disease herpesvirus induced neoplastic transformation of CD30 expressing lymphocytes in-vivo

BACKGROUND: Marek’s Disease (MD) is a hyperproliferative, lymphomatous, neoplastic disease of chickens caused by the oncogenic Gallid herpesvirus type 2 (GaHV-2; MDV). Like several human lymphomas the neoplastic MD lymphoma cells overexpress the CD30 antigen (CD30(hi)) and are in minority, while the...

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Detalhes bibliográficos
Main Authors: Kumar, Shyamesh, Kunec, Dusan, Buza, Joram J, Chiang, Hsin-I, Zhou, Huaijun, Subramaniam, Sugalesini, Pendarvis, Ken, Cheng, Hans H, Burgess, Shane C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472249/
https://ncbi.nlm.nih.gov/pubmed/22979947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-123
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