Transgenic Overexpression of Matrix Metalloproteinase-9 in Macrophages Attenuates the Inflammatory Response and Improves Left Ventricular Function Post-Myocardial Infarction

Following myocardial infarction (MI), activated macrophages infiltrate into the necrotic myocardium as part of a robust pro-inflammatory response and secrete matrix metalloproteinase-9 (MMP-9). Macrophage activation, in turn, modulates the fibrotic response, in part by stimulating fibroblast extrace...

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Detalhes bibliográficos
Main Authors: Zamilpa, Rogelio, Ibarra, Jessica, de Castro Brás, Lisandra E., Ramirez, Trevi A., Nguyen, Nguyen, Halade, Ganesh V., Zhang, Jianhua, Dai, Qiuxia, Dayah, Tariq, Chiao, Ying Ann, Lowell, Wesley, Ahuja, Seema S., D’Armiento, Jeanine, Jin, Yu-Fang, Lindsey, Merry L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472138/
https://ncbi.nlm.nih.gov/pubmed/22884843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2012.07.017
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