The Molecular Basis for Substrate Specificity of the Nuclear NIPP1:PP1 holoenzyme

Regulation of the Ser/Thr phosphatase protein phosphatase 1 (PP1) is controlled by a diverse array of regulatory proteins. However, how these proteins direct the specificity of PP1 is not well understood. More than 1/3 of the nuclear pool of PP1 forms a holoenzyme with the nuclear inhibitor of PP1,...

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Bibliografiske detaljer
Main Authors: O’Connell, Nichole, Nichols, Scott, Heroes, Ewald, Beullens, Monique, Bollen, Mathieu, Peti, Wolfgang, Page, Rebecca
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472097/
https://ncbi.nlm.nih.gov/pubmed/22940584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.08.003
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