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Flexibility in the PP1:spinophilin holoenzyme

Protein phosphatase 1 (PP1) interacts with ~200 regulatory proteins to form holoenzymes, which target PP1 to specific locations and regulate its specificity. While it is known that many PP1 regulatory proteins are dynamic in the unbound state, much less is known about the residual flexibility after...

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Dettagli Bibliografici
Autori principali: Ragusa, Michael J, Allaire, Marc, Nairn, Angus C., Page, Rebecca, Peti, Wolfgang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017638/
https://ncbi.nlm.nih.gov/pubmed/21094159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.11.022
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