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Flexibility in the PP1:spinophilin holoenzyme

Protein phosphatase 1 (PP1) interacts with ~200 regulatory proteins to form holoenzymes, which target PP1 to specific locations and regulate its specificity. While it is known that many PP1 regulatory proteins are dynamic in the unbound state, much less is known about the residual flexibility after...

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Detalhes bibliográficos
Main Authors: Ragusa, Michael J, Allaire, Marc, Nairn, Angus C., Page, Rebecca, Peti, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3017638/
https://ncbi.nlm.nih.gov/pubmed/21094159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2010.11.022
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