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Novel neurodevelopmental information revealed in amniotic fluid supernatant transcripts from fetuses with trisomies 18 and 21

Trisomies 18 and 21 are the two most common live born autosomal aneuploidies in humans. While the anatomic abnormalities in affected fetuses are well documented, the dysregulated biological pathways associated with the development of the aneuploid phenotype are less clear. Amniotic fluid (AF) cell-f...

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Autores principales: Hui, Lisa, Slonim, Donna K., Wick, Heather C., Johnson, Kirby L., Koide, Keiko, Bianchi, Diana W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472090/
https://ncbi.nlm.nih.gov/pubmed/22752091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-012-1195-x
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