Amniotic fluid transcriptomics reflects novel disease mechanisms in fetuses with myelomeningocele

BACKGROUND: Cell-free (cf) RNA in amniotic fluid supernatant (AFS) reflects developmental changes in gene expression in the living fetus, including genes specific to the central nervous system (CNS). Although it has been previously shown that CNS-specific transcripts are present in AFS, it is not kn...

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Veröffentlicht in:Am J Obstet Gynecol
Hauptverfasser: Tarui, Tomo, Kim, Aimee, Flake, Alan, Mcclain, Lauren, Stratigis, John, Fried, Inbar, Newman, Rebecca, Slonim, Donna K., Bianchi, Diana W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671344/
https://ncbi.nlm.nih.gov/pubmed/28735706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajog.2017.07.022
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