Enterohaemorrhagic E. coli (EHEC) exploits a tryptophan switch to hijack host F-actin assembly

Intrinsically disordered protein (IDP)-mediated interactions are often characterized by low affinity but high specificity. These traits are essential in signaling and regulation that require reversibility. Enterohaemorrhagic Escherichia coli (EHEC) exploit this situation by commandeering host cytosk...

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Hauptverfasser: Aitio, Olli, Hellman, Maarit, Skehan, Brian, Kesti, Tapio, Leong, John M., Saksela, Kalle, Permi, Perttu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472031/
https://ncbi.nlm.nih.gov/pubmed/22921828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2012.07.015
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