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A jumbo problem: mapping the structure and functions of the nuclear pore complex

Macromolecular assemblies can be intrinsically refractive to classical structural analysis, due to their size, complexity, plasticity and dynamic nature. One such assembly is the nuclear pore complex (NPC). The NPC is formed from ~450 copies of 30 different proteins, called nucleoporins, and is the...

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Detalles Bibliográficos
Main Authors: Fernandez-Martinez, Javier, Rout, Michael P
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3472030/
https://ncbi.nlm.nih.gov/pubmed/22321828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2011.12.013
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