Structure–function mapping of a heptameric module in the nuclear pore complex

The nuclear pore complex (NPC) is a multiprotein assembly that serves as the sole mediator of nucleocytoplasmic exchange in eukaryotic cells. In this paper, we use an integrative approach to determine the structure of an essential component of the yeast NPC, the ∼600-kD heptameric Nup84 complex, to...

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Detalhes bibliográficos
Main Authors: Fernandez-Martinez, Javier, Phillips, Jeremy, Sekedat, Matthew D., Diaz-Avalos, Ruben, Velazquez-Muriel, Javier, Franke, Josef D., Williams, Rosemary, Stokes, David L., Chait, Brian T., Sali, Andrej, Rout, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3283990/
https://ncbi.nlm.nih.gov/pubmed/22331846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201109008
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