Localising Loci underlying Complex Trait Variation Using Regional Genomic Relationship Mapping

The limited proportion of complex trait variance identified in genome-wide association studies may reflect the limited power of single SNP analyses to detect either rare causative alleles or those of small effect. Motivated by studies that demonstrate that loci contributing to trait variation may co...

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Autors principals: Nagamine, Yoshitaka, Pong-Wong, Ricardo, Navarro, Pau, Vitart, Veronique, Hayward, Caroline, Rudan, Igor, Campbell, Harry, Wilson, James, Wild, Sarah, Hicks, Andrew A., Pramstaller, Peter P., Hastie, Nicholas, Wright, Alan F., Haley, Chris S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471913/
https://ncbi.nlm.nih.gov/pubmed/23077511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046501
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