Radiating Amyloid Fibril Formation on the Surface of Lipid Membranes through Unit-Assembly of Oligomeric Species of α-Synuclein

BACKGROUND: Lewy body in the substantia nigra is a cardinal pathological feature of Parkinson's disease. Despite enormous efforts, the cause-and-effect relationship between Lewy body formation and the disorder is yet to be explicitly unveiled. METHODOLOGY/PRINCIPAL FINDINGS: Here, we showed tha...

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Main Authors: Lee, Jung-Ho, Hong, Chul-Suk, Lee, Soonkoo, Yang, Jee-Eun, Park, Yong Il, Lee, Daekyun, Hyeon, Taeghwan, Jung, Seunho, Paik, Seung R.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471876/
https://ncbi.nlm.nih.gov/pubmed/23077644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047580
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