Autocrine IFNγ Controls the Regulatory Function of Lymphoproliferative Double Negative T Cells

TCRαβ(+) CD4(−)CD8(−)NK(−) double negative T cells (DN T cells) can act as regulatory T cells to inhibit allograft rejection and autoimmunity. Their role in graft-versus-host disease and mechanisms of suppression remain elusive. In this study, we demonstrate that DN T cells can inhibit CD4(+) T cell...

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Detalhes bibliográficos
Main Authors: Juvet, Stephen C., Han, Mei, Vanama, Ramesh, Joe, Betty, Kim, Edward Y., Zhao, Fei Linda, Jeon, Caroline, Adeyi, Oyedele, Zhang, Li
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471870/
https://ncbi.nlm.nih.gov/pubmed/23077665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047732
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