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Autocrine IFNγ Controls the Regulatory Function of Lymphoproliferative Double Negative T Cells
TCRαβ(+) CD4(−)CD8(−)NK(−) double negative T cells (DN T cells) can act as regulatory T cells to inhibit allograft rejection and autoimmunity. Their role in graft-versus-host disease and mechanisms of suppression remain elusive. In this study, we demonstrate that DN T cells can inhibit CD4(+) T cell...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471870/ https://ncbi.nlm.nih.gov/pubmed/23077665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047732 |
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