Leukemia Inhibitory Factor Protects Axons in Experimental Autoimmune Encephalomyelitis via an Oligodendrocyte-Independent Mechanism

Leukemia inhibitory factor (LIF) and Ciliary Neurotrophic factor (CNTF) are members of the interleukin-6 family of cytokines, defined by use of the gp130 molecule as an obligate receptor. In the murine experimental autoimmune encephalomyelitis (EAE) model, antagonism of LIF and genetic deletion of C...

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Detalhes bibliográficos
Main Authors: Gresle, Melissa M., Alexandrou, Estella, Wu, Qizhu, Egan, Gary, Jokubaitis, Vilija, Ayers, Margaret, Jonas, Anna, Doherty, William, Friedhuber, Anna, Shaw, Gerry, Sendtner, Michael, Emery, Ben, Kilpatrick, Trevor, Butzkueven, Helmut
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471848/
https://ncbi.nlm.nih.gov/pubmed/23077604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0047379
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