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T-cell cloning to detect the mutant 6-thioguanine-resistant lymphocytes present in human peripheral blood.

Rare thioguanine-resistant T lymphocytes, present in vivo in human peripheral blood, were isolated and grown in vitro as thioguanine-resistant cultured T cells. The conditions for their selection in vitro were such that thioguanine resistance had to have arisen in vivo. The mutant cells bore T-cell...

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Detalhes bibliográficos
Main Authors: Albertini, R J, Castle, K L, Borcherding, W R
Formato: Artigo
Idioma:Inglês
Publicado em: 1982
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC347179/
https://ncbi.nlm.nih.gov/pubmed/6983072
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