Evidence for multiple origins of the beta E-globin gene in Southeast Asia.

To investigate whether recurrent mutation has contributed to the high frequency of the beta E-globin gene in Southeast Asia, we used the haplotypes at three polymorphic restriction sites within and to the 3' side of the beta-globin gene to predict the framework of 23 beta E-globin genes. These...

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Autores principales: Antonarakis, S E, Orkin, S H, Kazazian, H H, Goff, S C, Boehm, C D, Waber, P G, Sexton, J P, Ostrer, H, Fairbanks, V F, Chakravarti, A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1982
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC347177/
https://ncbi.nlm.nih.gov/pubmed/6292908
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