Cyclase-associated Protein (CAP) Acts Directly on F-actin to Accelerate Cofilin-mediated Actin Severing across the Range of Physiological pH

Fast actin depolymerization is necessary for cells to rapidly reorganize actin filament networks. Utilizing a Listeria fluorescent actin comet tail assay to monitor actin disassembly rates, we observed that although a mixture of actin disassembly factors (cofilin, coronin, and actin-interacting prot...

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Bibliographic Details
Main Authors: Normoyle, Kieran P. M., Brieher, William M.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2012
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471703/
https://ncbi.nlm.nih.gov/pubmed/22904322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.396051
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