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Autophagy-related Gene 7 (ATG7) and Reactive Oxygen Species/Extracellular Signal-regulated Kinase Regulate Tetrandrine-induced Autophagy in Human Hepatocellular Carcinoma

Tetrandrine, a bisbenzylisoquinoline alkaloid isolated from the broadly used Chinese medicinal herb Stephaniae tetrandrae, exhibits potent antitumor effects and has the potential to be used as a cancer chemotherapeutic agent. We previously reported that high concentrations of tetrandrine induce apop...

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Detalhes bibliográficos
Main Authors: Gong, Ke, Chen, Chao, Zhan, Yao, Chen, Yan, Huang, Zebo, Li, Wenhua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471698/
https://ncbi.nlm.nih.gov/pubmed/22927446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.370585
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