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Stable isotope-resolved metabolomics and applications for drug development

Advances in analytical methodologies, principally nuclear magnetic resonance spectroscopy (NMR) and mass spectrometry (MS), during the last decade have made large-scale analysis of the human metabolome a reality. This is leading to the reawakening of the importance of metabolism in human diseases, p...

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Главные авторы: Fan, Teresa W-M., Lorkiewicz, Pawel, Sellers, Katherine, Moseley, Hunter N.B., Higashi, Richard M., Lane, Andrew N.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471671/
https://ncbi.nlm.nih.gov/pubmed/22212615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2011.12.007
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