Sedlin Controls the ER Export of Procollagen by Regulating the Sar1 Cycle

Newly synthesized proteins exit the endoplasmic reticulum (ER) via coat protein complex II (COPII) vesicles. Procollagen (PC), however, forms prefibrils that are too large to fit into typical COPII vesicles; PC thus needs large transport carriers, which we term megacarriers. TANGO1 assists PC packin...

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Detalhes bibliográficos
Main Authors: Venditti, Rossella, Scanu, Tiziana, Santoro, Michele, Di Tullio, Giuseppe, Spaar, Alexander, Gaibisso, Renato, Beznoussenko, Galina V., Mironov, Alexander A., Mironov, Alexander, Zelante, Leopoldo, Piemontese, Maria Rosaria, Notarangelo, Angelo, Malhotra, Vivek, Vertel, Barbara M., Wilson, Cathal, De Matteis, Maria Antonietta
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471527/
https://ncbi.nlm.nih.gov/pubmed/23019651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224947
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