Microglial TIR-domain-containing adapter-inducing interferon-β (TRIF) deficiency promotes retinal ganglion cell survival and axon regeneration via nuclear factor-κB

BACKGROUND: TIR-domain-containing adapter-inducing interferon-β (TRIF) is the sole downstream adaptor of Toll-like receptor (TLR)3, which is one of the major signaling pathways in immune cells leading to neuroinflammation in the central nervous system. Overexpression of TRIF may lead to activation o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lin, Sen, Liang, Yajie, Zhang, Jiqiang, Bian, Chen, Zhou, Hongli, Guo, Qiang, Xiong, Ying, Li, Shurong, Su, Bingyin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2012
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471332/
https://ncbi.nlm.nih.gov/pubmed/22361049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-9-39
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