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p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage
Decitabine (DAC) and 5-azacitidine have recently been approved for the treatment of myelodysplastic syndrome. Thepharm acodynamic effects of DAC and 5-azacitidine outsidethe ir known activity as inhibitors of DNA methyltransferases (DNMTs) require further investigation. The purpose of this study was...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3471157/ https://ncbi.nlm.nih.gov/pubmed/18223691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1211018 |
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