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Cataleptic effects of γ-hydroxybutyrate (GHB) and baclofen in mice: mediation by GABA(B) receptors, but differential enhancement by N-methyl-d-aspartate (NMDA) receptor antagonists

RATIONALE: Gamma-hydroxybutyrate (GHB) is a gamma-aminobutyric acid (GABA) analog that is used to treat narcolepsy but that is also abused. GHB has many actions in common with the GABA(B) receptor agonist baclofen, but their underlying GABA(B) receptor mechanisms may be different. OBJECTIVE: The aim...

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Detalhes bibliográficos
Main Authors: Koek, Wouter, France, Charles P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470870/
https://ncbi.nlm.nih.gov/pubmed/18446324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-008-1160-5
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