Loss of Perivascular Kir4.1 Potassium Channels in the Sclerotic Hippocampus of Patients With Mesial Temporal Lobe Epilepsy

Recent experimental data in mice have shown that the inwardly rectifying K(+) channel Kir4.1 mediates K(+) spatial buffering in the hippocampus. Here we used immunohistochemistry to examine the distribution of Kir4.1 in hippocampi from patients with medication refractory temporal lobe epilepsy. The...

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Autors principals: Heuser, Kjell, Eid, Tore, Lauritzen, Fredrik, Thoren, Anna E., Vindedal, Gry F., Taubøll, Erik, Gjerstad, Leif, Spencer, Dennis D., Ottersen, Ole P., Nagelhus, Erlend A., de Lanerolle, Nihal C.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470834/
https://ncbi.nlm.nih.gov/pubmed/22878665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e318267b5af
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