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Retinoic Acid Protects Cardiomyocytes from High Glucose-Induced Apoptosis via Inhibition of Sustained Activation of NF-κB Signaling

We have previously shown that retinoic acid (RA) has protective effects on high glucose (HG)-induced cardiomyocyte apoptosis. To further elucidate the molecular mechanisms of RA effects, we determined the interaction between nuclear factor (NF)-κB and RA signaling. HG induced a sustained phosphoryla...

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Main Authors: Nizamutdinova, Irina T., Guleria, Rakeshwar S., Singh, Amar B., Kendall, Jonathan A., Baker, Kenneth M., Pan, Jing
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470832/
https://ncbi.nlm.nih.gov/pubmed/22718360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.24142
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