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High Glucose-Induced Repression of RAR/RXR In Cardiomyocytes is Mediated Through Oxidative Stress/JNK Signaling

The biological actions of retinoids are mediated by nuclear retinoic acid receptors (RARs) and retinoid × receptors (RXRs). We have recently reported that decreased expression of RARα and RXRα has an important role in high glucose (HG)-induced cardiomyocyte apoptosis. However, the regulatory mechani...

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Bibliographische Detailangaben
Hauptverfasser: Singh, Amar Bahadur, Guleria, Rakeshwar S., Nizamutdinova, Irina T., Baker, Kenneth M., Pan, Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258345/
https://ncbi.nlm.nih.gov/pubmed/21882190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.23005
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