AGO4 regulates entry into meiosis and influences silencing of sex chromosomes in the male mouse germ line

The four mammalian Argonaute family members are thought to share redundant functions in the microRNA pathway, yet only AGO2 possesses the catalytic “slicer” function required for RNA interference. Whether AGO1, AGO3, or AGO4 possess specialized functions remains unclear. Here we show that AGO4 local...

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Bibliografiske detaljer
Main Authors: Modzelewski, Andrew J., Holmes, Rebecca J., Hilz, Stephanie, Grimson, Andrew, Cohen, Paula E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470808/
https://ncbi.nlm.nih.gov/pubmed/22863743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.07.003
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