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Molecular targets in heart failure gene therapy: current controversies and translational perspectives

Gene therapy of heart failure is gaining momentum as a result of the recent successful completion of phase II of the CUPID trial, which showed clinical safety and efficacy of an adeno-associated viral vector expressing SERCA2a. Resorting to gene therapy allows the manipulation of molecular targets n...

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Autors principals: Kairouz, Victor, Lipskaia, Larissa, Hajjar, Roger J., Chemaly, Elie R.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470446/
https://ncbi.nlm.nih.gov/pubmed/22548568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06520.x
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