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Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria

Terpenoid metabolites are important to the cellular function, structural integrity, and pathogenesis of the human-specific pathogen Mycobacterium tuberculosis (Mtb). Genetic and biochemical investigations have indicated a role for the diterpenoid isotuberculosinol (isoTb) early in the infection proc...

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Detalhes bibliográficos
Main Authors: Mann, Francis M., Xu, Meimei, Davenport, Emily K., Peters, Reuben J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470408/
https://ncbi.nlm.nih.gov/pubmed/23091471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2012.00368
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