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SOS chromotest, a direct assay of induction of an SOS function in Escherichia coli K-12 to measure genotoxicity.
We present and evaluate the SOS chromotest, a bacterial test for detecting DNA-damaging agents. It is a colorimetric assay based on the induction by these agents of the SOS function sfiA, whose level of expression is monitored by means of a sfiA::lacZ operon fusion. The response is rapid (a few hour...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1982
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC347033/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6821127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.19.5971 |
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