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SOS chromotest, a direct assay of induction of an SOS function in Escherichia coli K-12 to measure genotoxicity.

We present and evaluate the SOS chromotest, a bacterial test for detecting DNA-damaging agents. It is a colorimetric assay based on the induction by these agents of the SOS function sfiA, whose level of expression is monitored by means of a sfiA::lacZ operon fusion. The response is rapid (a few hour...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Quillardet, P, Huisman, O, D'Ari, R, Hofnung, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1982
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC347033/
https://ncbi.nlm.nih.gov/pubmed/6821127
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