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Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance

Insulin resistance in skeletal muscle and liver may play a primary role in the development of type 2 diabetes mellitus, and the mechanism by which insulin resistance occurs may be related to alterations in fat metabolism. Transgenic mice with muscle- and liver-specific overexpression of lipoprotein...

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書目詳細資料
發表在:Proc Natl Acad Sci U S A
Principais autores: Kim, Jason K., Fillmore, Jonathan J., Chen, Yan, Yu, Chunli, Moore, Irene K., Pypaert, Marc, Lutz, E. Peer, Kako, Yuko, Velez-Carrasco, Wanda, Goldberg, Ira J., Breslow, Jan L., Shulman, Gerald I.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2001
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在線閱讀:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34701/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11390966/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121164498
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